Isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard

نویسندگان

  • Tianyang Li
  • Rui Jiang
  • Xuegong Zhang
چکیده

Maximum likelihood is a popular technique for isoform reconstruction. Here, we show that isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard.

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تاریخ انتشار 2013